ACTG2 Antikörper
Kurzübersicht für ACTG2 Antikörper (ABIN265300)
Target
Alle ACTG2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects endogenous levels of gamma 2 smooth muscle Actin / ACTG2 (Actin alpha-3/gamma-2) protein (region surrounding Glu2).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
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Applikationshinweise
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ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ACTG2 (Actin, gamma 2, Smooth Muscle, Enteric (ACTG2))
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Hintergrund
- All eukaryotic cells express actin, which often constitutes as much as 50 % of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of actin are present in mammalian tissues and fall into three classes. alpha actin expression is limited to various types of muscle, whereas beta and gamma are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the actin cytoskeleton. Rho controls the assembly of actin stress fibers and focal adhesion, Rac regulates actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.Synonyms: Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin
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Molekulargewicht
- approx. 45 kDa
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Gen-ID
- 72
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NCBI Accession
- NP_001186822
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UniProt
- P63267
Target
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