Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) Antikörper

Produktnummer ABIN265281

Der Kaninchen Polyklonal anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 Antikörper (ABIN265281) detektiert spezifisch Purinergic Receptor P2Y, G-Protein Coupled, 13 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) Antikörper (ABIN265281)

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Spezifität: This antibody detects P2Y13.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from human GPCR94

Anwendungsinformationen

Applikationshinweise: Western blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Antigendetails

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Andere Bezeichnung: P2Y13 / P2YR13

Hintergrund: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.Synonyms: FKSG77, G-protein coupled receptor 86, G-protein coupled receptor 94, GPR86, GPR94, P2Y purinoceptor 13, Purinergic receptor

Gen-ID: 53829

NCBI Accession: NP_795713

UniProt: Q9BPV8

Pathways: cAMP Metabolic Process