FBXW7 Antikörper
Kurzübersicht für FBXW7 Antikörper (ABIN265230)
Target
Alle FBXW7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects FBXW7, widely expressed in most tissues.
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Aufreinigung
- Purified
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Immunogen
- Synthetic peptide dervied from the human FBXW7 protein
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Drosophila melanogaster, Affe, Xenopus laevis, Hamster, Fledermaus, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 Reaktivität: Maus, Ratte, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 Reaktivität: Human WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
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Applikationshinweise
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Western Blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Andere Bezeichnung
- FBXW7
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Hintergrund
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
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Gen-ID
- 55294
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NCBI Accession
- NP_001013433
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UniProt
- Q969H0
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Pathways
- Notch Signalweg, EGFR Signaling Pathway
Target
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