CERS6 Antikörper
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- Target Alle CERS6 Antikörper anzeigen
- CERS6 (Ceramide Synthase 6 (CERS6))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CERS6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects Lass6, widely expressed. Expressed in kidney, liver, brain, heart, placenta and lung.
- Aufreinigung
- Purified
- Immunogen
- Synthetic peptide dervied from human Lass6 protein
- Top Product
- Discover our top product CERS6 Primärantikörper
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- Applikationshinweise
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Western blot (5-7 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- CERS6 (Ceramide Synthase 6 (CERS6))
- Andere Bezeichnung
- LASS6 (CERS6 Produkte)
- Synonyme
- si:ch211-278b7.1 antikoerper, CERS6 antikoerper, CERS5 antikoerper, LASS6 antikoerper, 4732462C07Rik antikoerper, AW544719 antikoerper, Lass6 antikoerper, T1L antikoerper, RGD1561599 antikoerper, ceramide synthase 6 antikoerper, CERS6 antikoerper, cers6 antikoerper, Cers6 antikoerper
- Hintergrund
- Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family. Five mammalian homologs have been reported, and the corresponding proteins have previously been investigated with respect to their key role in ceramide synthesis. However, members of the LAG family have been shown to be involved in cell growth regulation and cancer differentiation. May be involved in sphingolipid synthesis or its regulation. Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Localized to nuclear membrane a multi-pass membrane protein, may be expressed on endoplasmic reticulum membrane. Glycosylation on Asn-18 is not necessary for function. Like other LAG family members, the LASS6 protein contained a homeodomain and LAG1 domain. Lass6 displays highest homology to LASS5. The corresponding gene was localized to human chromosome 2q24.3, spanning a rather large genomic region of 318 kb. Sequences in mouse and zebrafish suggested a conservation of LASS6 in vertebrates because the protein and corresponding genomic sequences are highly conserved. LASS6 was shown to be broadly expressed in a wide range of tissues. Recent data suggested a role in cancer differentiation and early embryonic development.Synonyms: LAG1 longevity assurance homolog 6
- Gen-ID
- 253782
- NCBI Accession
- NP_982288
- UniProt
- Q6ZMG9
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