CD5L Antikörper (C-Term)

Produktnummer ABIN265124

Der Kaninchen Polyklonal anti-CD5L Antikörper wird verwendet zum Nachweis von CD5L in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für CD5L Antikörper (C-Term) (ABIN265124)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD5L Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to CD5L.

Aufreinigung: Purified

Immunogen: Rabbit polyclonal AIM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human AIM.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 2 μg/mL. Positive Control: Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver,but not in non-lymphoid tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Andere Bezeichnung: CD5L / API6

Hintergrund: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum -stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.Synonyms: AIM, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha

Gen-ID: 922

NCBI Accession: NP_005885

UniProt: O43866