Ceremide Kinase Antikörper

Produktnummer ABIN265118

Der Kaninchen Polyklonal anti-Ceremide Kinase Antikörper wird verwendet zum Nachweis von Ceremide Kinase in Proben von Human. Er wurde validiert für EIA und WB.

Kurzübersicht für Ceremide Kinase Antikörper (ABIN265118)

Target: Ceremide Kinase

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Enzyme Immunoassay (EIA), Western Blotting (WB)

Produktdetails

Aufreinigung: Purified

Immunogen: Recombinant full-length human ceramide kinase protein

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 10 μg/mL. Positive Control: High level expression in heart, brain, skeletal muscle, kidney and liver.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Antigendetails

Target: Ceremide Kinase

Hintergrund: Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondriamediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.Synonyms: Acylsphingosine kinase, LK4, Lipid kinase 4, hCERK