Sphingomyelin Synthase 1 Antikörper

Produktnummer ABIN265114

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Sphingomyelin Synthase 1 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Sphingomyelin Synthase 1 Antikörper (ABIN265114)

Target: Sphingomyelin Synthase 1 (SGMS1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sphingomyelin Synthase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper

Spezifität: This antibody reacts to Sphingomyelin Synthase 1.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the mouse sphingomyelin synthase 1 protein

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 5 - 10 μg/mL. Positive Control: Brain, heart, kidney, liver, muscle and stomach.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline, pH 7.4

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu Sphingomyelin Synthase 1

Target: Sphingomyelin Synthase 1 (SGMS1)

Andere Bezeichnung: TMEM23 / SGMS1

Hintergrund: A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.Synonyms: MOB, Medulla oblongata-derived protein, Phosphatidylcholine:ceramide cholinephosphotransferase 1, SMS1, Sphingomyelin synthase 1, Transmembrane protein 23

Gen-ID: 259230

NCBI Accession: NP_671512

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin