GNB5 Antikörper

Produktnummer ABIN265062

Der Kaninchen Polyklonal anti-GNB5 Antikörper (ABIN265062) detektiert spezifisch GNB5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GNB5 Antikörper (ABIN265062)

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GNB5 Antikörper

Spezifität: This antibody reacts to Gbeta5-D1.

Aufreinigung: Purified

Immunogen: Unique peptide sequence derived from the D1 blade of the Gbeta5 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu GNB5

Target: GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))

Andere Bezeichnung: Transducin beta Chain 5 (GNB5)

Hintergrund: The Gbeta5 protein is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gbeta5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas Gbeta1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in the Gbeta's 1 - 4.Synonyms: Gbeta5, Guanine nucleotide-binding protein subunit beta-5

Gen-ID: 10681

NCBI Accession: NP_006569

UniProt: O14775

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling