SUPT16H Antikörper (AA 1-329)
Kurzübersicht für SUPT16H Antikörper (AA 1-329) (ABIN265053)
Target
Alle SUPT16H Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-329
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Spezifität
- This antibody reacts to FACT complex subunit SPT16.
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Aufreinigung
- Purified
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Immunogen
- Recombinant protein consisting of amino acids 1 - 329 of the human SPT16 protein conjugated to GST.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Andere Bezeichnung
- SUPT16H / FACT140
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Hintergrund
- SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.Synonyms: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16
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Gen-ID
- 11198
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NCBI Accession
- NP_009123
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UniProt
- Q9Y5B9
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Pathways
- Chromatin Binding
Target
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