S1PR5 Antikörper (C-Term)

Produktnummer ABIN264983

Der Kaninchen Polyklonal anti-S1PR5 Antikörper wird verwendet zum Nachweis von S1PR5 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für S1PR5 Antikörper (C-Term) (ABIN264983)

Target: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-S1PR5 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to EDG8.

Aufreinigung: Purified

Immunogen: Unique synthetic peptide derived from the C-terminus of the human EDG-8 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL, detects recombinant EDG-8 receptors at 42 kDa, Due to lowexpression of EDG receptors, we recommend use of Pierce Femto Signal substrate forwestern blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu S1PR5

Target: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Andere Bezeichnung: EDG-8 / S1P5

Hintergrund: Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.Synonyms: EDG8, Endothelial differentiation G-protein-coupled receptor 8, S1P receptor 5, S1PR5, SPPR-1, SPPR-2

Gen-ID: 53637

NCBI Accession: NP_001159687

UniProt: Q9H228