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RED1 Antikörper (AA 6-66)

Dieses Anti-RED1-Antikörper ist ein Schaf Polyklonal-Antikörper zur Detektion von RED1 in WB und IF. Geeignet für Ratte. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN264972

Kurzübersicht für RED1 Antikörper (AA 6-66) (ABIN264972)

Target

Alle RED1 (ADARB1) Antikörper anzeigen
RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Reaktivität

  • 27
  • 19
  • 18
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 24
  • 4
  • 1
Schaf

Klonalität

  • 27
  • 2
Polyklonal

Konjugat

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RED1 Antikörper ist unkonjugiert

Applikation

  • 21
  • 7
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-66

    Spezifität

    This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).

    Aufreinigung

    Purified

    Immunogen

    GST fusion protein containing aa 6-66 of the rat RED1 coding sequence

    Isotyp

    IgG
  • Applikationshinweise

    Western Blot: 1: 1000. POSITIVE CONTROL: Rat Brain.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Yamashita, Chai, Teramoto, Tsuji, Shimazaki, Muramatsu, Kwak: "Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1710-9, (2013) (PubMed).

    Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).

  • Target

    RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

    Andere Bezeichnung

    ADARB1 / ADAR2

    Hintergrund

    RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.Synonyms: DRADA2, Double-stranded RNA-specific editase 1, RED1, RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase

    Molekulargewicht

    80.7 kDa

    Gen-ID

    25367

    NCBI Accession

    NP_001104525

    UniProt

    P51400
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