DAB1 Antikörper (C-Term)

Produktnummer ABIN264970

Dieses Schaf Polyklonal-Antikörper erkennt spezifisch DAB1 in WB und IP. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für DAB1 Antikörper (C-Term) (ABIN264970)

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reaktivität: Maus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser DAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-DAB1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to DAB1 (Disabled 1) (C Terminal).

Aufreinigung: Purified

Immunogen: Recombinant protein corresponding to amino acids 399 - 555 of mouse disabled coupled to a GST fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 μg/mL. Immunoprecipitation: 5 μg/mL. POSITIVE CONTROL: 293 cells transfected with Dab-1-HA tag.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Andere Bezeichnung: DAB1

Hintergrund: Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled-1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1

Gen-ID: 13131

NCBI Accession: NP_034144

UniProt: P97318