Malondialdehyde Antikörper (HRP)

Produktnummer ABIN264632

Der Ziege Polyklonal Anti-Malondialdehyde-Antikörper wurde für WB und EIA validiert. Er ist geeignet, Malondialdehyde in Proben von zu detektieren.

Kurzübersicht für Malondialdehyde Antikörper (HRP) (ABIN264632)

Target: Malondialdehyde (MDA)

Reaktivität: Bitte anfragen

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Malondialdehyde Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Malondialdehyde Antikörper (HRP)

Aufreinigung: MDA modified protein-Sepharose affinity column and conjugated with HRP

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1: 1,000 - 1: 4,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 0.5 mL distilled water. Centrifuge if not completely clear after standing for 1-2 hours at room temperature.

Konzentration: 1.2mg/mL (prior to lyophilization)

Buffer: Lyophilized from 50 mM PBS, 0.1 M Sodium Chloride, pH 7.4 containing 10 mg/mL BSA containing 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.

Details zu Malondialdehyde

Target: Malondialdehyde (MDA)

Andere Bezeichnung: Malondialdehyde / MDA

Substanzklasse: Chemical

Hintergrund: Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts.Synonyms: 1, 3-Propanedial, 3-Propanedione, Malondialdehyde Malonyldialdehyde, Malonic aldehyde, Malonic dialdehyde, Malonodialdehyde, Propanedial