SERPINC1 Antikörper

Produktnummer ABIN264614

Der Schaf Polyklonal Anti-SERPINC1-Antikörper wurde für IHC (p) und ID validiert. Er ist geeignet, SERPINC1 in Proben von Human, Maus, Ratte, Hund, Pferd und Cat zu detektieren.

Kurzübersicht für SERPINC1 Antikörper (ABIN264614)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Cat

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser SERPINC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunodiffusion (ID)

Produktdetails anti-SERPINC1 Antikörper

Spezifität: Antibody to Human Antithrombin III. This Antithrombin III antibody gives a single arc when tested by IEP against human plasma. Identity is confirmed by double diffusion (Ouchterlony) against human plasma and a known anti-human antithrombin III. The cross reactivity of this product against the sera of the species listed below has been assessed by double diffusion using 10 μL of antisera against 5 μL of species sera. These results are intended as a guideline only.

Aufreinigung: Ion Exchange Chromatography (DEAE); immunoelectrophoresis (IEP) and double diffusion

Immunogen: Human Antithrombin III purified from plasma, shown to be homogeneous by SDS-PAGE.

Anwendungsinformationen

Applikationshinweise: RID: 6l antiserum / cm2 gel vs.5 μL neat - 1/10 dilution human plasma. Double Diffusion: 10l antiserum vs.5l plasma. IEP: 100l antiserum vs.5l plasma. The use of 3 % PEG 6000 with 1.2 % agarose in a suitable buffer (such as TBE or Tris-barbital pH >8.2) is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 11.0 mg/mL (OD280nm, E1% = 14.5)

Buffer: Glycine buffered saline, pH 7.4 containing 0.099 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine, 1 mM EDTA

Konservierungsmittel: Sodium azide, Benzamidine, EACA

Vorsichtsmaßnahmen: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Andere Bezeichnung: SERPINC1 / Antithrombin-III

Hintergrund: Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160 mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58 kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties.Synonyms: AT3, ATIII, Serpin C1

Gen-ID: 462

NCBI Accession: NP_000479

UniProt: P01008