CCT2 Antikörper (C-Term)

Produktnummer ABIN264513

Dieses Anti-CCT2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CCT2 in WB und IHC (p). Geeignet für Human, Maus, Ratte und Frosch.

Kurzübersicht für CCT2 Antikörper (C-Term) (ABIN264513)

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Reaktivität: Human, Maus, Ratte, Frosch

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: F39 P7 F11

Produktdetails anti-CCT2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody recognizes T-Complex Protein 1, beta subunit.

Produktmerkmale: Synonyms: TCP1 Beta, CCT Beta, CCT-beta, CCTB, CCT2, 99D8.1, T-complex protein 1 subunit beta

Aufreinigung: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminal of the TCP-1β protein and mouse myelomaAg8563 cells. Sequence common in human, frog, mouse, rat.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. Positive Control: Colorectal cancer tissue, Calu6 and HT29 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.08 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CCT2

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Andere Bezeichnung: CCT2 / TCP1 beta

Hintergrund: The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species that are proposed to have independent functions in folding its in vivo substrates, the Actins and Tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.Synonyms: 99D8.1, CCT-beta, CCTB, T-complex protein 1 subunit beta, TCP-1 beta

Molekulargewicht: 57 kDa

Gen-ID: 10576

UniProt: P78371