TIMP2 Antikörper

Produktnummer ABIN264510

Dieses Anti-TIMP2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TIMP2 in WB, IHC (p) und EIA. Geeignet für Human, Maus, Zebrafisch (Danio rerio), Kaninchen, Schwein und Huhn.

Kurzübersicht für TIMP2 Antikörper (ABIN264510)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reaktivität: Human, Maus, Zebrafisch (Danio rerio), Kaninchen, Schwein, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 3A4

Produktdetails anti-TIMP2 Antikörper

Spezifität: This antibody recognizes Matrix Metalloproteinase 2 (TIMP2).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rabbit, Chicken, Zebrafish, Pig.
Species reactivity (tested):Human.

Produktmerkmale: Synonyms: TIMP-2, Tissue inhibitor of metalloproteinases 2, Metalloproteinase inhibitor 2, CSC-21K

Aufreinigung: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the human TIMP-2 protein and mouse myeloma Ag8563cells. Sequence common in mouse, rabbit, chicken, zebrafish and pig.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,95 mg/mL

Buffer: PBS, 0.08 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Andere Bezeichnung: TIMP2

Hintergrund: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation,branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CSC-21K, Metalloproteinase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2

Molekulargewicht: 18.5-21 kDa

Gen-ID: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process