TIMP1 Antikörper

Produktnummer ABIN264509

Der Maus Monoklonal Anti-TIMP1-Antikörper wurde für WB, EIA und IHC (fro) validiert. Er ist geeignet, TIMP1 in Proben von Human und Affe zu detektieren.

Kurzübersicht für TIMP1 Antikörper (ABIN264509)

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 2A5

Produktdetails anti-TIMP1 Antikörper

Spezifität: This antibody reacts to Tissue Inhibitor of Matrix Metalloproteinase 1.

Produktmerkmale: Synonyms: TIMP-1, TIMP, Tissue inhibitor of metalloproteinases, Metalloproteinase inhibitor 1, EPA,CLGI, Erythroid-potentiating activity, Fibroblast collagenase inhibitor

Aufreinigung: Purified

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Andere Bezeichnung: TIMP1

Hintergrund: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases

Gen-ID: 7076

UniProt: P01033