NPDC1 Antikörper

Produktnummer ABIN264467

Der Maus Monoklonal anti-NPDC1 Antikörper wird verwendet zum Nachweis von NPDC1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für NPDC1 Antikörper (ABIN264467)

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NPDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1-60E-005

Produktdetails anti-NPDC1 Antikörper

Spezifität: This antibody react to NPDC-1.

Produktmerkmale: Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

Aufreinigung: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with a syntheticpeptide derived from human NPDC-1 protein and mouse myeloma cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 1000. Positive Control: Brain tissue lysate (mouse and rat tested, human not yet tested).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu NPDC1

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Andere Bezeichnung: NPDC1

Hintergrund: The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

Gen-ID: 56654

UniProt: Q9NQX5