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S1PR4 Antikörper (C-Term)

Dieses Anti-S1PR4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von S1PR4 in WB, IF und FACS. Geeignet für Human.
Produktnummer ABIN264453

Kurzübersicht für S1PR4 Antikörper (C-Term) (ABIN264453)

Target

Alle S1PR4 Antikörper anzeigen
S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Reaktivität

  • 39
  • 30
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 49
  • 5
Maus

Klonalität

  • 51
  • 3
Monoklonal

Konjugat

  • 27
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser S1PR4 Antikörper ist unkonjugiert

Applikation

  • 39
  • 16
  • 13
  • 13
  • 9
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon

1
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Produktmerkmale

    Synonyms: S1P receptor 4, S1PR4, EDG6, LPC1, SLP4, Sphingosine 1-phosphate receptor 4, Endothelialdifferentiation G-protein coupled receptor 6

    Aufreinigung

    Purified

    Immunogen

    Hybridoma produced by the fusion of splenocytes from mice immunized with Uniquesynthetic peptide derived from the C-terminal of the EDG6 (S1P4) protein and mousemyeloma cells.

    Isotyp

    IgG1
  • Applikationshinweise

    Western Blot: 5-10 μg/mL. Flow Cytometry. Positive Control: RH7777 cells transfected with EDG-6 protein.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing containing 0.08 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.

    Haltbarkeit

    12 months
  • Target

    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

    Andere Bezeichnung

    S1PR4 / EDG6

    Hintergrund

    EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

    Gen-ID

    8698

    UniProt

    O95977
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