S1PR4 Antikörper (C-Term) (FITC)

Produktnummer ABIN264452

Der Maus Monoklonal Anti-S1PR4-Antikörper wurde für WB und FACS validiert. Er ist geeignet, S1PR4 in Proben von Human zu detektieren.

Kurzübersicht für S1PR4 Antikörper (C-Term) (FITC) (ABIN264452)

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S1PR4 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: 1

Produktdetails anti-S1PR4 Antikörper (FITC)

Bindungsspezifität: C-Term

Spezifität: Recognizes EDG-6/S1P4 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: S1P receptor 4, S1PR4, EDG6, LPC1, SLP4, Sphingosine 1-phosphate receptor 4, Endothelialdifferentiation G-protein coupled receptor 6

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with Uniquesynthetic peptide derived from the C-terminal of the EDG6 (S1P4) protein and mousemyeloma cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot. Flow Cytometry: Use 1 μg/10^6 cells. NOTE: Epitope for the antibody is the C-terminal of the EDG6 protein. The C-terminal is anintracellular region and cells need to be permeablized prior to staining with antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as a preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu S1PR4

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Andere Bezeichnung: S1PR4 / EDG6

Hintergrund: EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

Gen-ID: 8698

UniProt: O95977