SMC2 Antikörper (AA 523-768)

Produktnummer ABIN264446

Produktdetails anti-SMC2 Antikörper

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Bindungsspezifität: AA 523-768

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Recognizes SMC2/CAPE.

Produktmerkmale: Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-Ehomolog, Structural maintenance of chromosomes protein 2

Aufreinigung: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantprotein corresponding to amino acids 523-768 of Human CAP-E and Mouse myeloma cells. Genename: SMC2

Klon: E1M

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1-5 μg/mL. Positive Control/Tissue Expression: HeLa cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Andere Bezeichnung: SMC2 / CAPE (SMC2 Produkte)

Hintergrund: CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

Gen-ID: 10592

UniProt: O95347