KLRB1B Antikörper
Dieses Anti-KLRB1B-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von KLRB1B in FACS, IP und WB. Geeignet für Maus.
Produktnummer ABIN264402
Kurzübersicht für KLRB1B Antikörper (ABIN264402)
Target
KLRB1B
(Killer Cell Lectin-Like Receptor Subfamily B Member 1B (KLRB1B))
Reaktivität
Maus
Wirt
Maus
Klonalität
Monoklonal
Applikation
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
Klon
1C10
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Produktmerkmale
- Synonyms: NKRP1, Klrb1c NKR-P1
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Aufreinigung
- Purified
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Immunogen
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized (BALB/c XC57BL/6)F1 (CbyB6F1) lymphokine-activated killer (LAK) cells and mouse myeloma cell line.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot (1-5 μg/mL). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.08 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
Haltbarkeit
- 12 months
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- KLRB1B (Killer Cell Lectin-Like Receptor Subfamily B Member 1B (KLRB1B))
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Andere Bezeichnung
- Natural Killer Cell Receptor-P1
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Hintergrund
- Natural Killer (NK) cells are large, granular lymphocytes found primarily in peripheral blood, where they make up about 10 % of the lymphocyte population. Their function is to defend against certain types of tumor cells and virally infected cells. When triggered, the cells release cytotoxic granules which induce either apoptosis or necrosis in the target cell. There are known to be two sets of cell surface receptor on NK cells which recognize target cells with opposing functions. One set, of which an example is NKR-P1 receptors, trigger cytokine release and cell cytotoxicity and the other set, of which Ly49A is an example, inhibit cytokine release. These receptors bind with MHC class I molecules on the surface of healthy cells which inhibits the release of cytokines. In virally infected or cancerous cells, class I MHC molecules are not expressed, inducing the release of cytokine. An activation signal is known to exist, however the mechanics of this signal are not very well understood.Synonyms: Klrb1c NKR-P1, NKRP1
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UniProt
- Q61970
Target
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