NAPA Antikörper

Produktnummer ABIN264390

Der Maus Monoklonal anti-NAPA Antikörper (Klon 16D1) (ABIN264390) detektiert spezifisch NAPA in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh) und Huhn.

Kurzübersicht für NAPA Antikörper (ABIN264390)

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NAPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 16D1

Produktdetails anti-NAPA Antikörper

Spezifität: The antibody recognizes an epitope within the highly conserved domain between amino acids 109 - 193 of SNAP-alpha and SNAP-beta.

Produktmerkmale: Synonyms: SNAP-alpha, SNAPA, NAPA, Alpha-soluble NSF attachment protein

Aufreinigung: Standard chromatographic techniques.

Immunogen: Recombinant human alpha SNAP.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Suitable for use in Western Blot: 1/5000. Positive Control: Rat brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 20 mM Sodium Phosphate, 150 mM Sodium Chloride, 50 % Glycerol, pH 7.5

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu NAPA

Target: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Andere Bezeichnung: SNAP alpha

Hintergrund: 38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide- sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.Synonyms: Alpha-soluble NSF attachment protein, NAPA, SNAP-alpha, SNAPA

Gen-ID: 8775

UniProt: P54920

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization