OCT4 Antikörper

Produktnummer ABIN263989

Dieses Anti-OCT4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von OCT4 in IHC (p). Geeignet für Human.

Kurzübersicht für OCT4 Antikörper (ABIN263989)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OCT4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: NRG1-1

Produktdetails anti-OCT4 Antikörper

Spezifität: OCT-4 immunostaining has been shown to be a sensitive and specific marker for seminomatous / (dys)germinomatous tumours and in embryonal carcinoma variants of non-seminomatous GCTs, whether in primary gonadal or extragonadal sites or in metastatic lesions.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: POU5F1, OCT3, OCT4, OTF3, POU domain, class 5, transcription factor 1, Octamer-bindingtranscription factor 3, Oct-3, Oct-4

Aufreinigung: Purified

Immunogen: BALB/C mice injected with synthetic peptide of human OCT-4 origin.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry on Formalin fixed paraffin embedded tissue sections: 1/25-1/100 in an ABC method. Positive Control: Seminoma. Cellular Localization: Nuclear.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: Staining ProtocolWe suggest an incubation period of 30 minutes at room temperature. However, dependingupon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Details zu OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Andere Bezeichnung: OCT3/4

Hintergrund: OCT-4 (also known as POU5F1), a transcription factor that has been recognized as fundamental in the maintenance of pluripotency in embryonic stem cells and primordial germ cells, has been proposed as a useful marker for Germ Cell Tumors (GCTs) that exhibit features of pluripotentiality, specifically seminoma / dysgerminoma / germinoma and embryonal carcinoma.Synonyms: OCT3, OCT4, OTF3, Oct-3, Oct-4, Octamer-binding transcription factor 3, POU domain, POU5F1, class 5, transcription factor 1

Gen-ID: 5460

UniProt: Q01860

Pathways: Stem Cell Maintenance