Ferritin Antikörper (Heavy & Light Chain)

Produktnummer ABIN263729

Der Maus Monoklonal Anti-Ferritin-Antikörper wurde für EIA und ELISA (Detection) validiert. Er ist geeignet, Ferritin in Proben von Human zu detektieren.

Kurzübersicht für Ferritin Antikörper (Heavy & Light Chain) (ABIN263729)

Target: Ferritin (FE)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ferritin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: 090-10187

Produktdetails anti-Ferritin Antikörper

Bindungsspezifität: Heavy & Light Chain

Produktmerkmale: Synonyms: Ferritin H subunit, Ferritin L subunit, FTL, FTH

Aufreinigung: Protein A chromatography Product is 0.2 µm filtered

Immunogen: Ferritin from Human Spleen

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Recommended Pairs for Sandwich ImmunoassayCapture/Detection: ABIN263731 / ABIN263729ABIN263733 / ABIN263729
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 5.37 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 10 mM Phosphate, pH 7.4 containing 150 mM Sodium Chloride, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Ferritin

Target: Ferritin (FE)

Andere Bezeichnung: Ferritin

Hintergrund: Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis