ITGA4 Antikörper (APC)

Produktnummer ABIN2568299

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ITGA4 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für ITGA4 Antikörper (APC) (ABIN2568299)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA4 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: DATK32

Produktdetails anti-ITGA4 Antikörper (APC)

Spezifität: The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1).

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: LPAM-1

Hintergrund: The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa α4 and the 130 kDa β7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the α4β7 integrin heterodimer. α4β7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the α4β7 induces the α4β7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.

Gen-ID: 16401

UniProt: Q00651

Pathways: Integrin Complex