Fc epsilon RI/FCER1A Antikörper

Produktnummer ABIN2568133

Dieses Anti-Fc epsilon RI/FCER1A-Antikörper ist ein Hamster Monoklonal-Antikörper zur Detektion von Fc epsilon RI/FCER1A in FACS, IHC, IP und Func. Geeignet für Maus.

Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (ABIN2568133)

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser Fc epsilon RI/FCER1A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

Klon: FceR1

Produktdetails anti-Fc epsilon RI/FCER1A Antikörper

Spezifität: The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu Fc epsilon RI/FCER1A

Target: Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Andere Bezeichnung: Fc epsilon Receptor I alpha

Hintergrund: The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.

Gen-ID: 2205

UniProt: P12319

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process