CD8 alpha Antikörper (PE-Cy5)
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- Target Alle CD8 alpha (CD8A) Antikörper anzeigen
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 alpha Antikörper ist konjugiert mit PE-Cy5
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The 53-6.7 monoclonal antibody specifically reacts with Ly-2, the 38 kDa alpha chain, and with Lyt-2, the 34 kDa alpha' chain, of the mouse CD8 antigen.
- Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Klon
- 53-6-7
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CD8A Primärantikörper
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anti-CD8a Molecule (CD8A) (AA 22-235) antibody
CD8A Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 8H8A8 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Maus FACS, IP, IHC (fro), IHC (p), ICC, Func Wirt: Ratte Monoclonal 53-6-7 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Maus FACS, IP, IHC (fro), IHC (p), ICC Wirt: Ratte Monoclonal 53-6-7 unconjugated
anti-CD8a Molecule (CD8A) antibody (FITC)CD8A Reaktivität: Maus FACS Wirt: Ratte Monoclonal 53-6-7 FITC
anti-CD8a Molecule (CD8A) antibody (PE)CD8A Reaktivität: Maus FACS Wirt: Ratte Monoclonal 53-6-7 PE
anti-CD8a Molecule (CD8A) (AA 51-150) antibodyCD8A Reaktivität: Human, Ratte, Huhn FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Human IHC, WB, IP, ELISA Wirt: Kaninchen Monoclonal 2F2 unconjugated Recombinant Antibody
anti-CD8a Molecule (CD8A) (AA 22-182) antibodyCD8A Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 6A9A5 unconjugated
anti-CD8a Molecule (CD8A) antibodyCD8A Reaktivität: Human IHC, StM, ISt Wirt: Maus Monoclonal C8-468 unconjugated
anti-CD8a Molecule (CD8A) (AA 28-196) antibodyCD8A Reaktivität: Maus, Ratte FACS, IHC, WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Andere Bezeichnung
- CD8a (CD8A Produkte)
- Hintergrund
- The 53-6.7 monoclonal antibody specifically reacts with Ly-2, the 38 kDa alpha chain, and with Lyt-2, the 34 kDa alpha' chain, of the mouse CD8 antigen. The alpha' chain is the truncated form of alpha chain, encoded by the same CD8a gene. In CD8a, the alpha and alpha' chains form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b.CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. Its function seems to be to attenuate the CD8-mediated signal for the stimulation of intrathymic T-cell maturation.The 53-6.7 antibody is useful for depleting CD8+ peripheral T lymphocytes. It cross reacts with the alpha- and alpha'-like polypeptides on some thymic and peripheral lymphocytes.
- Gen-ID
- 12525
- UniProt
- P01731
- Pathways
- T-Zell Rezeptor Signalweg
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