Der PE-konjugierte Maus Monoklonal anti-P-Selectin Antikörper (Klon AK-4) (ABIN2567887) detektiert spezifisch P-Selectin in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM).
Aufreinigung
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Andere Bezeichnung
CD62P
Hintergrund
The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.