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L-Selectin Antikörper (FITC)

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch L-Selectin in FACS. Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN2567876

Kurzübersicht für L-Selectin Antikörper (FITC) (ABIN2567876)

Target

Alle L-Selectin (SELL) Antikörper anzeigen
L-Selectin (SELL) (Selectin L (SELL))

Reaktivität

  • 113
  • 75
  • 47
  • 35
  • 10
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
Ratte

Wirt

  • 111
  • 70
  • 55
  • 3
  • 1
Ratte

Klonalität

  • 183
  • 51
  • 4
Monoklonal

Konjugat

  • 91
  • 26
  • 20
  • 14
  • 13
  • 8
  • 6
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser L-Selectin Antikörper ist konjugiert mit FITC

Applikation

  • 168
  • 76
  • 76
  • 73
  • 39
  • 28
  • 23
  • 21
  • 10
  • 8
  • 8
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

MEL-14
  • Spezifität

    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains.

    Aufreinigung

    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.5 mg/mL

    Buffer

    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target

    L-Selectin (SELL) (Selectin L (SELL))

    Andere Bezeichnung

    CD62L

    Substanzklasse

    Chemical

    Hintergrund

    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin, 74 kDa on lymphocytes or 95 kDa on neutrophils. In the mouse organism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes. After cell activation, it is quickly shed by neutrophils and lymphocytes.

    Gen-ID

    20343

    UniProt

    P18337
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