Integrin beta 3 Antikörper
Kurzübersicht für Integrin beta 3 Antikörper (ABIN2567868)
Target
Alle Integrin beta 3 (ITGB3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.
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Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The product should be stored undiluted at 4°C. Do not freeze.
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- Integrin beta 3 (ITGB3)
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Andere Bezeichnung
- CD61
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Hintergrund
- The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
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Gen-ID
- 3690
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UniProt
- P05106
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
Target
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