ICAM1 Antikörper
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- Target Alle ICAM1 Antikörper anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ICAM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
- Spezifität
- The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1).
- Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Klon
- 15-2
- Isotyp
- IgG1
- Top Product
- Discover our top product ICAM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- CD54 (ICAM1 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- The 15.2 antibody reacts with the 85-110 kDa intracellular adhesion molecule-1 (ICAM-1), a member of the Ig superfamily which acts as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). ICAM-1 is also known CD 54 and is expressed on non-hematopoietic cells of vascular endothelial, thymic epithelial, fibroblasts lineages, and on hematopoietic cells like macrophages, mitogen-stimulated T-lymphoblasts, dendritic cells in tonsils, lymph nodes and Peyer's patches, and germinal center B cells.Inflammatory mediators (IL-1, TNF, IFN-γ) enhance the production of ICAM-1 on fibroblasts and endothelial cells within few hours. Thus, ICAM-1 seems to be the marker of inflammatory reactions.
- Gen-ID
- 3383
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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