CD4 Antikörper (PE-Cy7)
Kurzübersicht für CD4 Antikörper (PE-Cy7) (ABIN2567661)
Target
Alle CD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV).
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Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
- The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
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Gen-ID
- 920
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UniProt
- P01730
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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