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CD28 Antikörper

CD28 Reaktivität: Maus FACS, IP, Func Wirt: Hamster Monoclonal 37-51 unconjugated

Produktnummer ABIN2567434

Datenblatt (PDF)

Target Alle CD28 Antikörper anzeigen

CD28
Reaktivität
181

115

53

37

22

16

12

12

7

7

7

6

2

1

1

1

1

1
Maus
Wirt
152

76

32

12

10

3

2
Hamster
Klonalität
212

68

4
Monoklonal
Konjugat
109

31

27

20

15

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD28 Antikörper ist unkonjugiert
Applikation
214

89

59

50

41

35

34

26

23

17

13

7

7

6

6

6

5

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

37-51

Isotyp

IgG

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CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

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CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD28

Andere Bezeichnung

CD28 (CD28 Produkte)

Hintergrund

The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer. It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells. It is additionally found on activated splenocytes, mast cells, and thymocytes. CD 28 is a costimulator of T lymphocytes and a ligand for CD80 (B7-1), and CD86 (B7-2). The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.

Gen-ID

12487

UniProt

P31041

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response