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CD28 Antikörper (APC)

CD28 Reaktivität: Human FACS Wirt: Maus Monoclonal CD28-2 APC

Produktnummer ABIN2567432

Datenblatt (PDF)

Target Alle CD28 Antikörper anzeigen

CD28
Reaktivität
181

118

53

37

22

16

12

12

7

7

7

6

2

1

1

1

1

1
Human
Wirt
154

76

33

12

10

3

2
Maus
Passende Sekundärantikörper
Klonalität
215

68

4
Monoklonal
Konjugat
110

32

28

20

15

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD28 Antikörper ist konjugiert mit APC
Applikation
217

89

60

50

41

35

35

26

23

17

13

7

7

6

6

6

5

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

CD28-2

Isotyp

IgG1 kappa

Top Product

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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD28

Andere Bezeichnung

CD28 (CD28 Produkte)

Hintergrund

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 Molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.

Gen-ID

920

UniProt

P10747

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response