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CD28 Antikörper

CD28 Reaktivität: Human FACS, IP, Func, IHC Wirt: Maus Monoclonal CD28-2 unconjugated

Produktnummer ABIN2567423

Datenblatt (PDF)

Target Alle CD28 Antikörper anzeigen

CD28
Reaktivität
181

116

53

37

22

16

12

12

7

7

7

6

2

1

1

1

1

1
Human
Wirt
152

76

33

12

10

3

2
Maus
Passende Sekundärantikörper
Klonalität
213

68

4
Monoklonal
Konjugat
110

31

27

20

15

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD28 Antikörper ist unkonjugiert
Applikation
215

89

60

50

41

35

35

26

23

17

13

7

7

6

6

6

5

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (IHC)

Spezifität

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

CD28-2

Isotyp

IgG1 kappa

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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD28

Andere Bezeichnung

CD28 (CD28 Produkte)

Hintergrund

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 Molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.

Gen-ID

920

UniProt

P10747

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response