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CD16 Antikörper

CD16 Reaktivität: Maus FACS, IF, IP, Func Wirt: Ratte Monoclonal 2-4G2 unconjugated

Produktnummer ABIN2567263

Datenblatt (PDF)

Target Alle CD16 Antikörper anzeigen

CD16
Reaktivität
145

26

21

21

21

9

9

8

8

4

3

3

2

2

2

2

2

2

2

2

2

2
Maus
Wirt
127

25

19

1
Ratte
Passende Sekundärantikörper
Klonalität
147

23

1
Monoklonal
Konjugat
63

19

14

14

9

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD16 Antikörper ist unkonjugiert
Applikation
139

34

29

26

26

25

21

18

6

6

5

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

2-4G2

Isotyp

IgG2b

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anti-CD16 (CD16) (AA 17-208) antibody
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anti-CD16 (CD16) antibody
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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD16

Andere Bezeichnung

CD16 (CD16 Produkte)

Hintergrund

The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc γ I receptor.

Gen-ID

14131

UniProt

P08508

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process