CILP Antikörper (AA 1051-1184)
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- Target Alle CILP Antikörper anzeigen
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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Bindungsspezifität
- AA 1051-1184
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CILP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CILP
- Isotyp
- IgG
- Top Product
- Discover our top product CILP Primärantikörper
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anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 603-846) antibody
CILP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 604-864) antibodyCILP Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reaktivität: Human ELISA Wirt: Maus Monoclonal 2D10 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP Reaktivität: Human ELISA Wirt: Maus Monoclonal 2C5 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (Internal Region) antibodyVerified CILP Reaktivität: Ratte WB, ELISA Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- Andere Bezeichnung
- CILP (CILP Produkte)
- Hintergrund
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Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188
Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
- Gen-ID
- 8483
- UniProt
- O75339
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