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CHMP2A Antikörper (AA 1-100) (Biotin)

Dieses Anti-CHMP2A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHMP2A in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Ratte.
Produktnummer ABIN2559697

Kurzübersicht für CHMP2A Antikörper (AA 1-100) (Biotin) (ABIN2559697)

Target

Alle CHMP2A Antikörper anzeigen
CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

Reaktivität

  • 27
  • 20
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 39
  • 2
Kaninchen

Klonalität

  • 41
Polyklonal

Konjugat

  • 12
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CHMP2A Antikörper ist konjugiert mit Biotin

Applikation

  • 32
  • 15
  • 13
  • 13
  • 10
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 2
    • 2
    • 1
    • 1
    AA 1-100

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Sheep

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CHMP2A

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

    Andere Bezeichnung

    CHMP2A

    Hintergrund

    Synonyms: BC2, BC-2, VPS2, CHMP2, VPS2A, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, CHMP2a, Putative breast adenocarcinoma marker BC-2, Vacuolar protein sorting-associated protein 2-1, Vps2-1, hVps2-1

    Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

    Gen-ID

    27243

    UniProt

    O43633

    Pathways

    SARS-CoV-2 Protein Interaktom
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