DHRS2 Antikörper (AA 61-160) (Biotin)

Produktnummer ABIN2559683

Produktdetails anti-DHRS2 Antikörper (Biotin)

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Bindungsspezifität: AA 61-160

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHRS2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHRS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DHRS2

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Andere Bezeichnung: DHRS2 (DHRS2 Produkte)

Synonyme: DHRS2 antikoerper, HEP27 antikoerper, SDR25C1 antikoerper, 5430405K24Rik antikoerper, Hep27 antikoerper, dehydrogenase/reductase 4 antikoerper, dehydrogenase/reductase 2 antikoerper, dehydrogenase/reductase member 2 antikoerper, DHRS4 antikoerper, DHRS2 antikoerper, Dhrs2 antikoerper

Hintergrund:

Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Gen-ID: 10202

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process