COMP Antikörper (AA 221-320) (HRP)
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- Target Alle COMP Antikörper anzeigen
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
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Bindungsspezifität
- AA 221-320
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COMP Antikörper ist konjugiert mit HRP
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human COMP
- Isotyp
- IgG
- Top Product
- Discover our top product COMP Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- Andere Bezeichnung
- COMP (COMP Produkte)
- Synonyme
- COMP antikoerper, EDM1 antikoerper, EPD1 antikoerper, MED antikoerper, PSACH antikoerper, THBS5 antikoerper, TSP5 antikoerper, cartilage oligomeric matrix protein antikoerper, COMP antikoerper, sce3551 antikoerper, CJA_1292 antikoerper, Comp antikoerper
- Hintergrund
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Synonyms: MED, EDM1, EPD1, PSACH, THBS5, Cartilage oligomeric matrix protein, COMP, Thrombospondin-5, TSP5
Background: May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity).
- Gen-ID
- 1311
- UniProt
- P49747
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