Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) Antikörper
Kurzübersicht für Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) Antikörper (ABIN2559496)
Target
Alle Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-120
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Cow,Sheep
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human GRF2
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)
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Andere Bezeichnung
- GRF2
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Hintergrund
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Synonyms: GRF2, RAS-GRF2, Ras-specific guanine nucleotide-releasing factor 2, Ras guanine nucleotide exchange factor 2, RASGRF2
Background: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
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Gen-ID
- 5924
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UniProt
- O14827
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Pathways
- Neurotrophin Signalübertragung
Target
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