Aquaporin 1 Antikörper (N-Term) (Atto 488)

Produktnummer ABIN2486435

Dieses Anti-Aquaporin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aquaporin 1 in WB, IHC, IF und ICC. Geeignet für Ratte.

Kurzübersicht für Aquaporin 1 Antikörper (N-Term) (Atto 488) (ABIN2486435)

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aquaporin 1 Antikörper ist konjugiert mit Atto 488

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Aquaporin 1 Antikörper (Atto 488)

Bindungsspezifität: N-Term

Spezifität: Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein A Purified

Immunogen: Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1

Anwendungsinformationen

Applikationshinweise:

• WB (1:2000)
• IHC (1:200)
• ICC/IF (1:400)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.5 μg/ml of ABIN2486435 was sufficient for detection of aquaporin 1 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu Aquaporin 1

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Andere Bezeichnung: Aquaporin 1

Hintergrund: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).

Gen-ID: 25240

NCBI Accession: NP_036910

UniProt: P29975

Pathways: Hormone Transport