NPAS4 Antikörper (AA 597-802) (APC)
Kurzübersicht für NPAS4 Antikörper (AA 597-802) (APC) (ABIN2485816)
Target
Alle NPAS4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 597-802
-
Spezifität
- Highly expressed in the brain, with lower expression found in endocrine tissue.,Detects ~90 kDa.
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Aufreinigung
- Protein G Purified
-
Immunogen
- Fusion protein amino acids 597-802 (C-terminus) of rat Npas4.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
- WB (1:1000)
- ICC/IF(1:100)
- optimal dilutions for assays should be determined by the user.
-
Kommentare
-
A 1:100 dilution of ABIN2485816 was sufficient for detection of NPAS4 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
-
-
- NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))
-
Andere Bezeichnung
- NPAS4
-
Hintergrund
- NPAS4 belongs to the Per-Arnt-Sim family of neuronal specific transciption factors, all involved in the development and maintenance of learning and memory pathways (1). NPAS4 is a transcription factor that regulates the formation and maintenance of inhibitory synapses, and can activate the CNS midline enhancer element and the expression of the drebrin gene. Deregulation has been to be associated with developmental disorders such as schizophrenia and autism (2).
-
Gen-ID
- 266734
-
NCBI Accession
- NP_705890
-
UniProt
- Q8CJH6
Target
-