TRPC5 Antikörper (AA 827-845) (PerCP)
Kurzübersicht für TRPC5 Antikörper (AA 827-845) (PerCP) (ABIN2485382)
Target
Alle TRPC5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 827-845
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Spezifität
- Detects ~110 kDa.
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Protein G Purified
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Immunogen
- Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)
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Isotyp
- IgG2b
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Applikationshinweise
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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1 μg/ml of ABIN2485382 was sufficient for detection of TrpC5 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))
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Andere Bezeichnung
- TRPC5
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Hintergrund
- Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin (1). This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol (2).
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Gen-ID
- 7224
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NCBI Accession
- NP_036603
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UniProt
- Q9UL62
Target
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