TRPV3 Antikörper (AA 458-474) (PerCP)
Kurzübersicht für TRPV3 Antikörper (AA 458-474) (PerCP) (ABIN2485246)
Target
Alle TRPV3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 458-474
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Spezifität
- Detects ~70 kDa.
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Protein G Purified
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Immunogen
- Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
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Isotyp
- IgG2a
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Applikationshinweise
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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1 μg/ml of ABIN2485246 was sufficient for detection of TrpV3 in 10 μg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))
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Andere Bezeichnung
- TRPV3
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Hintergrund
- The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).
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Gen-ID
- 497948
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NCBI Accession
- NP_001020928
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UniProt
- Q4QYD9
Target
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