ADRA2C Antikörper (AA 442-462) (APC)
Kurzübersicht für ADRA2C Antikörper (AA 442-462) (APC) (ABIN2485207)
Target
Alle ADRA2C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 442-462
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Spezifität
- Detects 50 kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Protein G Purified
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Immunogen
- Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
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Isotyp
- IgG1
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Applikationshinweise
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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1 μg/ml of ABIN2485207 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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Andere Bezeichnung
- Alpha2C Adrenergic
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Hintergrund
- The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
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Gen-ID
- 152
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NCBI Accession
- NP_000674
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UniProt
- P18825
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Pathways
- EGFR Signaling Pathway, cAMP Metabolic Process
Target
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