ADRA2C Antikörper (AA 442-462) (Atto 488)

Produktnummer ABIN2485199

Dieses Anti-ADRA2C-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ADRA2C in WB, ICC und IF. Geeignet für Human.

Kurzübersicht für ADRA2C Antikörper (AA 442-462) (Atto 488) (ABIN2485199)

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADRA2C Antikörper ist konjugiert mit Atto 488

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: S330A-80

Produktdetails anti-ADRA2C Antikörper (Atto 488)

Bindungsspezifität: AA 442-462

Spezifität: Detects 50 kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.

Kreuzreaktivität: Human, Maus

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2485199 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Andere Bezeichnung: Alpha2C Adrenergic

Hintergrund: The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.

Gen-ID: 152

NCBI Accession: NP_000674

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process