TRAP1 Antikörper

Produktnummer ABIN2484668

Dieses Anti-TRAP1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TRAP1 in WB, IF und ICC. Geeignet für Human.

Kurzübersicht für TRAP1 Antikörper (ABIN2484668)

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 3H4-2H6

Produktdetails anti-TRAP1 Antikörper

Spezifität: Detects ~75 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Purified recombinant TRAP1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2484668 was sufficient for detection of Trap-1/HSP75 in 20 μg of Human A431 lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu TRAP1

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Andere Bezeichnung: TRAP1

Hintergrund: The 90 kDa heat shock protein (HSP90) family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to be associated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting pre-sequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).

Gen-ID: 10131

NCBI Accession: NP_057376

UniProt: Q12931