CDC37 Antikörper (Biotin)

Produktnummer ABIN2484525

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDC37 in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CDC37 Antikörper (Biotin) (ABIN2484525)

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC37 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-CDC37 Antikörper (Biotin)

Spezifität: Detects ~44.5 kDa.

Kreuzreaktivität: Human

Aufreinigung: Protein A Purified

Immunogen: Native human Cdc37, full length

Anwendungsinformationen

Applikationshinweise:

• WB (1:2000)
• ICC/IF (1:200)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:2000 dilution of ABIN2484525 was sufficient for detection of cdc37 in 20 μg of HeLa cell lysate by ECL immunoblot analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.68 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Andere Bezeichnung: CDC37

Hintergrund: HSP90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with HSP90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing HSP90 to its target kinases (1, 2). CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies (3, 4).

Gen-ID: 11140

NCBI Accession: NP_008996

UniProt: Q16543